Mayim IRL
Believe it or not, Mayim’s first on-screen appearance wasn’t TBBT. She started acting in 1987, with her debut title being the TV drama series Beauty and the Beast. She even played a cameo role in the spin-off series Young Sheldon. As of right now, Mayim is busy with her new sitcom series called Call me Kat, where she plays the leading role.
What made her perfect for playing Amy was that she’s actually a neuroscientist. While research may not always pay the bills, the cool $1 million she took home for every episode certainly did.