Melissa Rauch (Bernadette Rostenkowski-Wolowitz)
Microbiologist Bernadette Rostenkowski first appeared alongside the TBBT gang in the show’s third season. Penny introduces Bernadette, who works with her at The Cheesecake Factory, to Howard. Initially, the pair feel they have little in common, but when they learn about each other’s overbearing mothers, we instantly know they were meant for each other.
In the fourth season, Howard finally pops the question to Bernadette, and the two officially tie the knot in the following season. While it’s clear that their backgrounds couldn’t be more different, their on-screen chemistry gave hope to all nerdy guys out there that there’s someone for everyone.